Title: Synthesis of CuO and Ag doped CuO nanoparticles from Muntingia calabura leaf extract and evaluation of their antimicrobial potential

Authors: Kiran Kumar Prem Kumar; Nandipura D. Dinesh; Satish Kumar Murari

Addresses: Department of Chemistry, ATME College of Engineering, 13th Kilometer Mysore-Kanakapura Bangalore Road, Mysuru, 570028, Karnataka State, India ' Department of Chemistry, Adichunchanagiri Institute of Technology, Chikkamagaluru, Karnataka State, India ' Department of Chemistry, P.E.S. College of Engineering, Mandya, 571401, Karnataka State, India

Abstract: The present study explored Muntingia calabura leaf extract as a reducing and capping agent for synthesis of CuO as well as Ag doped CuO nanoparticles. The role of terpenoids and polyols of the plant extract in reduction and stabilisation of both doped and undoped nanoparticles was confirmed on an infrared spectrum. Subsequently, the crystal structure transformed from monoclinic to cubic system and increased in size. While CuO nanoparticles exhibited maximum absorption in the UV range, doping with Ag resulted in enhanced absorbance in the visible range as well as a reduction in band gap energy. Zeta potential values approached the threshold of delicate dispersion and increased with Ag doping. Broader size distribution and relatively reduced agglomeration among doped nanoparticles could be observed. Differential antimicrobial effects of doped and undoped nanoparticles against selected strains of bacteria and fungi were confirmed.

Keywords: antimicrobial activity; CuO/Ag nanoparticles; Muntingia calabura leaf extract; green synthesis; capping agent.

DOI: 10.1504/IJNBM.2019.104939

International Journal of Nano and Biomaterials, 2019 Vol.8 No.3/4, pp.228 - 252

Received: 25 Oct 2018
Accepted: 09 Apr 2019
Published online: 07 Feb 2020 *

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