Title: Effect of repetitive transcranial magnetic stimulation on motor function and spasticity in spastic cerebral palsy

Authors: Meena Gupta; Bablu Lal Rajak; Dinesh Bhatia; Arun Mukherjee

Addresses: Department of Biomedical Engineering, North Eastern Hill University, Shillong, Meghalaya, India ' Department of Biomedical Engineering, North Eastern Hill University, Shillong, Meghalaya, India ' Department of Biomedical Engineering, North Eastern Hill University, Shillong, Meghalaya, India ' UDAAN for the Differently Abled, Lajpat Nagar, New Delhi, 110024, India

Abstract: In this study, 20 sCP participants were selected and were divided equally into two groups - control group (CG) and experimental group (EG). Ten participants in CG (mean age 8.11+SD4.09) were given physical therapy for 30 minutes daily for 20 days and those in EG (mean age 7.93+SD4.85) were administered 5Hz r-TMS frequency for 15 minutes consisting of 1,500 pulses daily followed by physical therapy of same duration as provided to CG. Modified Ashworth scale (MAS) and gross motor function measure (GMFM) were used as outcome measures. The pre- and post-assessment were completed in both study groups and their statistical analysis was found to be significant (p < 0.05). The GMFM result shows EG have 1.95% improvement as compared to 0.55% in CG also MAS score of EG showed significant spasticity reduction in muscles of lower extremity as compared to participants in CG.

Keywords: motor disability; spasticity; spastic cerebral palsy; sCP; physical therapy; transcranial magnetic stimulation; TMS.

DOI: 10.1504/IJBET.2019.103251

International Journal of Biomedical Engineering and Technology, 2019 Vol.31 No.4, pp.365 - 374

Received: 18 Jan 2017
Accepted: 17 May 2017
Published online: 23 Oct 2019 *

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