Forthcoming and Online First Articles

Atoms for Peace: an International Journal

Atoms for Peace: an International Journal (AFP)

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Atoms for Peace: an International Journal (1 paper in press)

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  • Assessment of the dosimetric index from IMRT and RapidArc plan for oropharyngeal cancer with simultaneous integrated boost technique in combination with EUD-based NTCP and TCP radiobiological models.   Order a copy of this article
    by Sougoumarane Dashnamoorthy, Ebenezar Jeyasingh, Karthick Rajamanickam 
    Abstract: The current research compared radiobiological and dosimetric results for simultaneous integrated boost plans employing RapidArc and IMRT planning procedures in oropharyngeal cancer from head-and-neck cancer patients. The indigenously developed Python-based software was used in this study for generation and analysis. Twelve patients with forty-eight total plans with SIB were planned using Rapid arc (2 and 3 arcs) and IMRT (7 and 9 fields) and compared with radiobiological models Lyman Kutcher Burman and Equivalent Uniform Dose along with physical index such as homogeneity index, conformity index. These inputs from these models are the dose-volume histograms calculated by the treatment planning system. The values obtained vary from one model to the other for the same technique and patient. The maximum dose to the brainstem and spinal cord and the mean dose to the parotids were analysed both dosimetrically and radiobiologically, such as the Lyman Kutcher Burman model effective volume, equivalent uniform dose, equivalent uniform dose based normal tissue complication probability, and normal tissue integral dose.
    Keywords: DVH; 3DCRT; IMRT; RapidArc; NTCP; TCP; EUD; Python.
    DOI: 10.1504/AFP.2023.10061434
     

 

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