Title: Mechanical bio-pump as a functional component of a ventricular assist system: haemodynamic-modelling study and fluid-structure solution Author: Gustavo Suárez; Yvon Maday; John Bustamante Addresses: Cardiovascular Dynamics Research Group, Universidad Pontificia Bolivariana, Medellín, Colombia Laboratoire Jacques-Louis Lions, Pierre et Marie Curie University, Paris, France Cardiovascular Dynamics Research Group, Universidad Pontificia Bolivariana, Circular 1, No. 70-01, Bloq. 22, 050031 Medellín, Colombia Journal: Int. J. of Biomedical Engineering and Technology, 2015 Vol.19, No.2, pp.169 - 186 Abstract: Simulated experience was performed through a computational haemodynamic fluid-structure solution, with the implementation of a mechanical bio-pump as a functional element of a ventricular assistance device, in which the mechanical dynamics of latissimus dorsi muscle is represented. The influence of chamber geometry and constituent material parameters is evaluated upon the pumping functionality. By analysis of haemodynamic variables, it is found that geometry and elasticity are parameters influencing the determination of the pump outflow. In conclusion, the computational haemodynamic model helps evaluate the mechanical behaviour of the functional cardiac assist device through haemodynamic variables. Keywords: ventricular assistance devices; haemodynamic modelling; fluid-structure solution; cardiovascular modelling; numerical simulation; mechanical bio-pumps; muscle dynamics; latissimus dorsi muscle; chamber geometry; material parameters; elasticity; pump outflow; haemodynamics; fluid dynamics; blood flow; bioengineering; biomechanics; heart rate. DOI: http://dx.doi.org/10.1504/IJBET.2015.072935 Available online 08 Nov 2015
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