Title: Development of a numerical model for single red blood cell motions in stationary fluid in the presence of uniform magnetic field

Authors: Kazuya Tatsumi; Yuki Komori; Tomoki Arakawa; Kosuke Nishitani; Kazuyoshi Nakabe

Addresses: Department of Mechanical Engineering, and Science, Kyoto University, Yoshida-Honmachi, Sakyo-ku, Kyoto, Kyoto 606-8501, Japan ' Department of Mechanical Engineering, and Science, Kyoto University, Yoshida-Honmachi, Sakyo-ku, Kyoto, Kyoto 606-8501, Japan ' Department of Mechanical Engineering, and Science, Kyoto University, Yoshida-Honmachi, Sakyo-ku, Kyoto, Kyoto 606-8501, Japan ' Department of Mechanical Engineering, and Science, Kyoto University, Yoshida-Honmachi, Sakyo-ku, Kyoto, Kyoto 606-8501, Japan ' Department of Mechanical Engineering, and Science, Kyoto University, Yoshida-Honmachi, Sakyo-ku, Kyoto, Kyoto 606-8501, Japan

Abstract: Development of a three dimensional numerical model which considers the effects of the uniform magnetic field on the phospholipids and transmembrane proteins of the red blood cell (RBC) suspended in fluid is described in this study. Visualisation measurement of the RBC motion characterised by the inclination angle of the RBC is also carried out by using the microchannel and high-speed camera to validate the numerical results. Further, the distribution of the magnetic forces on the membrane in relation to the RBC motion, and the evaluation of the overall anisotropic diamagnetic susceptibility of the RBC using the numerical results are discussed.

Keywords: red blood cells; RBC; strong uniform magnetic field; rotational motion; stationary fluids; numerical modelling; elastic spring model; fluid-cell conjugate problem; immersed boundary method; visualisation measurement; microchannels; 3D modelling; magnetic forces; cell motion; anisotropic diamagnetic susceptibility.

DOI: 10.1504/PCFD.2013.053663

Progress in Computational Fluid Dynamics, An International Journal, 2013 Vol.13 No.3/4, pp.224 - 237

Published online: 31 Oct 2013 *

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