The protection afforded by vitamin D against low radiation damage Online publication date: Wed, 29-Oct-2008
by Daniel P. Hayes
International Journal of Low Radiation (IJLR), Vol. 5, No. 4, 2008
Abstract: Our general understanding and appreciation of the multifaceted protective actions of vitamin D have recently entered a new era. It is now becoming recognised that its most active molecular form, 1,25-dihydroxyvitamin D3 (also known as calcitriol), may offer protection against a variety of radiation- and otherwise-induced damages. As will be discussed, vitamin D carries out its protective actions by a host of mechanisms, among these being cell cycle regulation and proliferation, cellular differentiation and communication, Programmed Cell Death (PCD) (apoptosis and autophagy) and antiangiogenesis. As will be proposed and developed, vitamin D, with its preventative/ameliorating actions, should be considered among the prime (if not the primary) nonpharmacological agents that offer protection against sublethal low radiation damage and, in particular, against radiation-induced cancer.
Online publication date: Wed, 29-Oct-2008
Go to Inderscience Online Journals to access the Full Text of this article.
If you are not a subscriber and you just want to read the full contents of this article, buy online access here.Complimentary Subscribers, Editors or Members of the Editorial Board of the International Journal of Low Radiation (IJLR):
Login with your Inderscience username and password:
Want to subscribe?
A subscription gives you complete access to all articles in the current issue, as well as to all articles in the previous three years (where applicable). See our Orders page to subscribe.
If you still need assistance, please email email@example.com