Title: Application of ensemble artificial neural network for the classification of white blood cells using microscopic blood images

Authors: Jyoti Rawat; Annapurna Singh; H.S. Bhadauria; Jitendra Virmani; Jagtar Singh Devgun

Addresses: Department of Computer Science and Engineering, GB Pant Engineering College, Pauri Garhwal, 246194, Uttarakhand, India ' Department of Computer Science and Engineering, GB Pant Engineering College, Pauri Garhwal, 246194, Uttarakhand, India ' Department of Computer Science and Engineering, GB Pant Engineering College, Pauri Garhwal, 246194, Uttarakhand, India ' Council of Scientific and Industrial Research, Central Scientific Instruments Organisation, Sec-30 C, 160030, Chandigarh, India ' M.M. Institute of Medical Sciences and Research, Department of Pathology, Solan, Himachal Pradesh, India

Abstract: In order to overcome the problems of manual diagnosis in recognising the morphology of blood cells, the automated analysis is frequently used by a pathologist. So this work gives a semi-automated technique to identify and classify white blood cell. In this work, a k-means clustering algorithm is used to segment the nucleus by upgrading the district of the white blood cell nucleus and stifling the other components of the blood smear images. From each cell, various shape, chromatic and texture features are extracted. This feature set was used to train the classifier to determine different classes of WBC. Performance of this model indicates that CAC system design based on the ensemble artificial neural network is the most suitable model for the four class white cell classification, with an accuracy of 95%. The proposed method represents a medicinal method to avoid the plentiful drawbacks associated with the labour-intensive examination of WBCs.

Keywords: white blood cell; segmentation; k-means clustering; texture features; shape features; chromatic features; artificial neural network classifier; ANN.

DOI: 10.1504/IJCSYSE.2018.091407

International Journal of Computational Systems Engineering, 2018 Vol.4 No.2/3, pp.202 - 216

Received: 02 Oct 2016
Accepted: 11 Jun 2017
Published online: 30 Apr 2018 *

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