Title: An improved unsupervised mapping technique using AMSOM for neurodegenerative disease detection

Authors: Isha Suwalka; Navneet Agrawal

Addresses: College of Technology and Engineering, Maharana Pratap University of Agriculture and Technology, Udaipur, Rajasthan, India ' College of Technology and Engineering, Maharana Pratap University of Agriculture and Technology, Udaipur, Rajasthan, India

Abstract: The most challenging aspect in medical imaging is the accuracy of detection of neurodegenerative diseases. The advent of new imaging techniques has yet limited manual evaluations, manual reorientation and other time consuming limitations with reduced resolution. Therefore, there is a need to develop efficient algorithm for proper detection with quantitative information of significance for the clinicians. The proposed algorithm includes improved adaptive moving self organising mapping (AMSOM) which trains the extracted features along with mini-mental state examination (MMSE) factor and volumetric parameter using volume-based method (VBM) for computing feature dataset which in total improves time iteration rate, mean square error, sensitivity and accuracy. The algorithm is an improved version of moving mapping method which on one hand tackles drawback of SOM of fixed grid mapping and improves neighbourhood function of neuron which provides better detection and classification yielding promising results. It further improves performance of AMSOM by better visualisation of the input dataset and provides a framework for determining the efficient parameters. This paper uses real MRI dataset taken from OASIS having a cross-sectional collection of 416 subjects aged 18 to 96. The analysis includes different comparison of mapping approaches that reveals features associated to the Alzheimer disease.

Keywords: self organising mapping for MRI image; hierarchical mapping with GHSOM; e-database using OASIS; moving neuron concept using AMSOM; clustering for detection of Alzheimer disease.

DOI: 10.1504/IJCSYSE.2018.091402

International Journal of Computational Systems Engineering, 2018 Vol.4 No.2/3, pp.185 - 194

Received: 24 Oct 2016
Accepted: 04 Jun 2017
Published online: 30 Apr 2018 *

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