Title: Towards effects estimation of ethical medicine from the package inserts with text mining

Authors: Takashi Ikoma; Yoshikatsu Fujita; Masakazu Takahashi; Kazuhiko Tsuda

Addresses: Graduate School of Business Sciences, University of Tsukuba, Tokyo 3-29-1, Otsuka, Bunkyo-ku 112-0012, Japan ' Department of Sociology, Teikyo University, 359 Otsuka, Hachioji, Tokyo 192-0395, Japan ' Graduate School of Innovation and Technology Management, Yamaguchi University 2-16-1 Tokiwadai, Ube, Yamaguchi 755-8611, Japan ' Graduate School of Business Sciences, University of Tsukuba, Tokyo 3-29-1, Otsuka, Bunkyo-ku 112-0012, Japan

Abstract: Various experimental data can be found in the package inserts of ethical medicines, because it is mandated by the supervisory agency in Japan. This is open information and available for everyone. If we analyse the information contained in the package inserts by text mining, it is possible to evaluate the effects of the ethical medicines quantitatively. In this study, we chose antipyretic effects as sample cases. Then, we looked at the experimental background consisting of experiment method and experiment itself, to find the difference. The ethical medicine type and experimental data were summarised for each of experimental background. The effect of the ethical medicine was suggested that it was possible to narrow the effective range when extracted for each of experimental background. In the same manner, the effect's ratio between any medicines were to be inferred without direct comparison.

Keywords: package inserts; ethical medicines; effect range; experimental configuration; quantitative comparison research; text mining; experimental background; Japan; antipyretic effects.

DOI: 10.1504/IJISTA.2015.074324

International Journal of Intelligent Systems Technologies and Applications, 2015 Vol.14 No.3/4, pp.188 - 204

Received: 10 Apr 2015
Accepted: 16 Sep 2015
Published online: 22 Jan 2016 *

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