Title: Mining and analysing scale-free protein–protein interaction network

Authors: Xiaohua Hu

Addresses: College of Information Science and Technology, Drexel University, Philadelphia, PA 19104, USA

Abstract: Protein–protein interaction network is essential to understand the fundamental processes that govern cell biology. In this paper, we integrate information extraction and data mining techniques to extract and mine the scale-free protein–protein interaction network from biomedical literature. The experiments on around 1,600 chromatin proteins indicate that our system is very promising for mining and analysing protein–protein interaction network.

Keywords: scale-free network graph; protein–protein interaction; biomedical literature; data mining; clustering; chromatin proteins; information extraction; information retrieval; bioinformatics; computational biology.

DOI: 10.1504/IJBRA.2005.006904

International Journal of Bioinformatics Research and Applications, 2005 Vol.1 No.1, pp.81 - 101

Published online: 21 Apr 2005 *

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