Title: Dosimetry analysis of two new design 103Pd interstitial brachytherapy sources

Authors: Pooneh Saidi; Mahdi Sadeghi; Alireza Shirazi; Seied Rabie Mahdavi; Mohammad Mirzaii

Addresses: Nuclear Engineering Department, Science and Research Branch, Islamic Azad University, Tehran, Iran. ' Agricultural, Medical and Industrial Research School, Science and Technology Research Institute, Karaj, Iran. ' Medical Physics Department, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran. ' Medical Physics Department, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran. ' Agricultural, Medical and Industrial Research School, Science and Technology Research Institute, Karaj, Iran

Abstract: With increased demand for low 103Pd (palladium) seed sources, to treat prostate and eye cancers, new sources have been designed and introduced. This paper presents the two new palladium brachytherapy sources, IR03-103Pd and IR04-103Pd that have been developed at Agricultural, Medical & Industrial Research School. The dosimetric parameters, such as the dose rate constant &923;, the radial dose function g(r) and the anisotropy function F(r, θ), around the sources have been characterised using Version 5 Monte Carlo radiation transport code in accordance with the update AAPM Task Group No. 43 Report (TG-43U1). The results indicated the dose rate constant of 0.689 ± 0.02 and 0.667 ± 0.02 cGy h−1 U−1 for the IR03-103Pd and IR04-103Pd sources, respectively, which are in acceptable agreement with other commercial seeds. The calculated results were compared with published results for those of other source manufacturers. However, they show an acceptable dose distribution, using for clinical applications is pending experimental dosimetry.

Keywords: Monte Carlo radiation transport code; palladium brachytherapy; TG-43U1; MCNP5; low radiation; prostate cancer; eye cancer; dose distribution; brachytherapy sources.

DOI: 10.1504/IJLR.2011.047177

International Journal of Low Radiation, 2011 Vol.8 No.5/6, pp.363 - 373

Received: 23 Jul 2011
Accepted: 07 Nov 2011

Published online: 07 Feb 2015 *

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