Title: Role of the left ventricular cavity-to-myocardium count ratio in resting technetium-99m-Sestamibi SPECT in the recovery of myocardial function after thrombolytic therapy in patients with acute myocardial infarction

Authors: A.I. Neshandar, M.A. Porpiranfar, S.M.R. Aghamiri, H. Javadi

Addresses: Department of Nuclear Medicine, Taleghani Hospital, Shahid Beheshti University of Medical Science, Tehran, Iran. ' Department of Cardiology, Taleghani Hospital, Shahid Beheshti University of Medical Science, Tehran, Iran. ' Taleghani Hospital, Shahid Beheshti University of Medical Science, Tehran, Iran. ' Department of Nuclear Medicine, Taleghani Hospital, Shahid Beheshti University of Medical Science, Tehran, Iran

Abstract: The aim of this study was to assess the value of the Cavity-to-Myocardium count ratio (CM ratio) calculated in the resting 99mTc-Sestamibi SPECT images to identify myocardial functioning status and recovery of myocardial function in patients with acute myocardial insult who have received thrombolytic therapy. The study demonstrates that the resting 99mTc-Sestamibi SPECT CM ratio can be used to approximately assess the left ventricular function status and can predict the recovery of jeopardised myocardium function after thrombolytic therapy.

Keywords: technetium-99m-Sestamibi; streptokinase; myocardial infarction; cavity-to-myocardial ratio; SPECT; myocardial function recovery; thrombolytic therapy; left ventricular function.

DOI: 10.1504/IJLR.2007.014487

International Journal of Low Radiation, 2007 Vol.4 No.1, pp.33 - 42

Published online: 11 Jul 2007 *

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