Title: Identification of novel Phytophthora infestans small RNAs involved in potato late blight reveals potential cross-kingdom regulation to facilitate oomycete infection

Authors: Haowu Chang; Hao Zhang; Qing-Ming Qin; Tianyue Zhang; Teng Zhang; Yuanning Liu; Haiming Liu; Xiaodan Zhong; Shizeng Song; Cong Li; Bowen Shen

Addresses: College of Computer Science and Technology & Symbol Computation and Knowledge Engineering, Ministry of Education, Jilin University, Changchun 130012, Jilin, China ' College of Computer Science and Technology & Symbol Computation and Knowledge Engineering, Ministry of Education, Jilin University, Changchun 130012, Jilin, China ' College of Plant Sciences and Key Laboratory of Zoonosis Research, Ministry of Education, Jilin University, Changchun 130012, Jilin, China ' College of Computer Science and Technology & Symbol Computation and Knowledge Engineering, Ministry of Education, Jilin University, Changchun 130012, Jilin, China ' College of Computer Science and Technology & Symbol Computation and Knowledge Engineering, Ministry of Education, Jilin University, Changchun 130012, Jilin, China ' College of Computer Science and Technology & Symbol Computation and Knowledge Engineering, Ministry of Education, Jilin University, Changchun 130012, Jilin, China ' College of Computer Science and Technology & Symbol Computation and Knowledge Engineering, Ministry of Education, Jilin University, Changchun 130012, Jilin, China ' College of Computer Science and Technology & Symbol Computation and Knowledge Engineering, Ministry of Education, Jilin University, Changchun 130012, Jilin, China ' College of Computer Science and Technology & Symbol Computation and Knowledge Engineering, Ministry of Education, Jilin University, Changchun 130012, Jilin, China ' College of Computer Science and Technology & Symbol Computation and Knowledge Engineering, Ministry of Education, Jilin University, Changchun 130012, Jilin, China ' College of Computer Science and Technology & Symbol Computation and Knowledge Engineering, Ministry of Education, Jilin University, Changchun 130012, Jilin, China

Abstract: Potato late blight, caused by the oomycete Phytophthora infestans, is one of the most devastating potato diseases. However, the pathogenesis of the oomycete pathogen remains mostly obscure. Small RNAs (sRNAs) of fungal pathogens and host plants have proven to be closely related to their interactions. Based on analysing differentially expressed sRNA data before and after infection of P. infestans, this paper obtains potential transboundary regulation fungus sRNAs and analyses their essential characteristics and functions. The result shows that sRNAs of the oomycete pathogen P. infestans likely possess the capacity of cross-kingdom regulation of potato growth and defence. The prediction model of P. infestans sRNAs related to the cross-kingdom regulation and pathogenic process provides a new analytical approach for the study of host infection by oomycete pathogens and contributes to our understanding of the interaction between oomycete pathogens and their host plants.

Keywords: late blight; oomycete pathogens; Phytophthora infestans; sRNA; cross-kingdom regulation; random forest; fungus-plant interaction.

DOI: 10.1504/IJDMB.2020.107379

International Journal of Data Mining and Bioinformatics, 2020 Vol.23 No.2, pp.119 - 141

Received: 31 Jul 2019
Accepted: 02 Jan 2020

Published online: 22 May 2020 *

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