Title: A Grid-Based Pseudo-Cache solution for MISD biomedical problems with high confidentiality and efficiency

Authors: Yuan-Shun Dai, Mathew Palakal, Shielly Hartanto, Xiaolong Wang, Yanming Guo

Addresses: Department of Computer and Information Science, Purdue University School of Science, Indiana University-Purdue University, Indianapolis, 723 W. Michigan Street SL 280, Indianapolis, Indiana 46202-5132, USA. ' Department of Computer and Information Science, Purdue University School of Science, Indiana University-Purdue University, Indianapolis, 723 W. Michigan Street SL 280, Indianapolis, Indiana 46202-5132, USA. ' Department of Computer and Information Science, Purdue University School of Science, Indiana University-Purdue University, Indianapolis, 723 W. Michigan Street SL 280, Indianapolis, Indiana 46202-5132, USA. ' Department of Computer and Information Science, Purdue University School of Science, Indiana University-Purdue University, Indianapolis, 723 W. Michigan Street SL 280, Indianapolis, Indiana 46202-5132, USA. ' Department of Computer and Information Science, Purdue University School of Science, Indiana University-Purdue University, Indianapolis, 723 W. Michigan Street SL 280, Indianapolis, Indiana 46202-5132, USA

Abstract: The complexity of most biomedical/bioinformatics problems requires efficient solutions using collaborative/parallel computing. One promising solution is to implement Grid computing, as an emerging new field called BioGrid. However, one of the most stringent requirements in such a Grid-based solution is data privacy. This paper presents a novel solution to provide the Confidentiality when using the Grid to efficiently solve MISD biomedical problems. It is called the Grid-Based Pseudo-Cache (GBPC) solution. It is proved to have equal or better performance than traditional MIMD solution. Via case studies our theories are validated in practice, and the data dependence is also addressed.

Keywords: biomedical information; bioinformatics; grid computing; data privacy; efficiency; confidentiality; multiple instruction single dataset; pseudo-cache.

DOI: 10.1504/IJBRA.2006.010604

International Journal of Bioinformatics Research and Applications, 2006 Vol.2 No.3, pp.259 - 281

Published online: 07 Aug 2006 *

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