Title: Hybrid deep learning approach for improving the diagnosis of lung cancer disease

Authors: Shaik Bhasha; B.N. Jagadesh

Addresses: School of Computer Science and Engineering, VIT-AP University, Amaravati, Andhra Pradesh, 522237, India ' School of Computer Science and Engineering, VIT-AP University, Amaravati, Andhra Pradesh, 522237, India

Abstract: Lung cancer is recognised as the most severe disease that affects humans and frequently results in mortality when compared to other cancer conditions. Lung cancer cannot be detected early because it exhibits no symptoms. However, early identification of lung cancer contributes to people's continued survival rate. Computer technology has recently been employed to solve these diagnostic issues. In this research, we propose a hybrid deep-learning method for predicting lung cancer. An enhanced MobileNetV3 (EMobileNetV3) is proposed to predict the probability of lung cancer. The DenseNet-169 model is used to extract the features. An effective osprey optimisation algorithm (Os-OA) is also presented to adjust the proposed classification model's parameters to improve the classification performance. Compared to other existing models, the proposed model performed better, obtaining an accuracy of 98% and an AUC of 96% for dataset 1 and an accuracy of 99.30% and an AUC of 96.6% for dataset 2.

Keywords: deep learning; mean imputation; min-max scaling; DenseNet-169; EMobileNetV3.

DOI: 10.1504/IJBET.2026.151420

International Journal of Biomedical Engineering and Technology, 2026 Vol.50 No.1, pp.55 - 86

Received: 30 Sep 2024
Accepted: 21 Feb 2025
Published online: 28 Jan 2026 *

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