Bionanosilver-poly (methyl 2-methylpropenoate) electrospun nanofibre as a potent antibacterial against multidrug resistant bacteria
by M.A. Abu-Saied; E.E. Hafez; T.H. Taha; Khalil Abdelrazek Khalil
International Journal of Nanoparticles (IJNP), Vol. 7, No. 3/4, 2014

Abstract: Poly (methyl 2-methylpropenoate) PMMA [(C5O2H8)n] and bionanosilver are known to have inhibitory and bactericidal effects. In this study, Bacillus subtilis was used to produce bionanosilver particles that were characterised using SEM and FE-SEM. The bionanosilver were mixed with PMMA and dissolving in dimethylformamide (DMF) to produce bionanosilver-nanofibre (bionanofibre) using electrospun. The surface morphology was investigated by SEM. The activity of bionanofibre was examined as antibacterial against nine human pathogenic bacteria and the results were compared with different generic antibiotics. The bionanofibre showed high antibacterial activity and it was found that bionanofibre more specific for Methicillin-resistant Staphylococcus aureus (MRSA) especially in liquid culture with low concentrations.

Online publication date: Sat, 28-Feb-2015

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