Bioinformatics tools for genome-wide single nucleotide polymorphisms management and analyses: a review
by Qiongying Jia; Yanqi Wu; Nongyue He; Yan Deng
International Journal of Bio-Inspired Computation (IJBIC), Vol. 6, No. 3, 2014

Abstract: Advances in modern genetics have brought a dramatic increase in the number of single nucleotide polymorphisms (SNPs), as well as the fast accumulating genotype data in public databases. In response, many bioinformatics tools are explored to manage and extract valuable information from such large datasets. Here, we firstly review the methodological strategies and introduce some well-established programs in management and analyses of SNP data. Then, possible challenges and development in this field are discussed. It hopes that these applied tools will greatly assist in exploring susceptibility for complex diseases.

Online publication date: Sat, 27-Sep-2014

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