Near-infrared imaging of balb/c mice injected with a detoxified botulinum neurotoxin A
by Martha Hale, Stephen Riding, Bal Ram Singh
The Botulinum J. (TBJ), Vol. 1, No. 4, 2010

Abstract: Identifying pathways taken by Botulinum Neurotoxins (BoNTs) in vivo is an important step to delineate therapeutic windows of opportunity and design countermeasures against them. Because of their high toxicity, tracking the toxin's biodistribution has not been possible. The current preliminary report showed that the toxin's movement in vivo could be followed by using a non-toxic version of type A botulinum neurotoxin (drBoNT/A) labelled with a dye that fluoresces in the Near-Infrared (NIR) spectrum.

Online publication date: Thu, 17-Mar-2011

The full text of this article is only available to individual subscribers or to users at subscribing institutions.

Existing subscribers:
Go to Inderscience Online Journals to access the Full Text of this article.

Pay per view:
If you are not a subscriber and you just want to read the full contents of this article, buy online access here.

Complimentary Subscribers, Editors or Members of the Editorial Board of the The Botulinum J. (TBJ):
Login with your Inderscience username and password:

    Username:        Password:         

Forgotten your password?

Want to subscribe?
A subscription gives you complete access to all articles in the current issue, as well as to all articles in the previous three years (where applicable). See our Orders page to subscribe.

If you still need assistance, please email