Title: Identification of protein-coding regions using Modified Gabor-Wavelet Transform with Signal Boosting Technique

Authors: Malaya Kumar Hota, Vinay Kumar Srivastava

Addresses: Department of Electronics and Communication Engineering, Motilal Nehru National Institute of Technology, Allahabad 211004, Uttar Pradesh, India. ' Department of Electronics and Communication Engineering, Motilal Nehru National Institute of Technology, Allahabad 211004, Uttar Pradesh, India

Abstract: Modified Gabor-Wavelet Transform (MGWT) has been previously used for identification of protein coding regions. This method does not significantly suppress the non-coding regions which may result incorrect identification. To enhance the discrimination between the coding and non-coding regions of the DNA sequence, Signal Boosting Technique (SBT) is applied on the projection coefficients which are obtained by applying MGWT. The performance of the proposed Modified Gabor-Wavelet Transform with Signal Boosting Technique (MGWT-SBT) is compared with other existing methods such as MGWT, Short-Time Discrete Fourier Transform (ST-DFT), anti-notch filter and multi-stage filter. Results show that the proposed method gives better identification accuracy as compared to other methods.

Keywords: MGWT; modified Gabor-wavelet transform; SBT; signal boosting technique; protein coding regions; ST-DFT; short-time discrete Fourier transform; anti-notch filters; multi-stage filters; computational biology.

DOI: 10.1504/IJCBDD.2010.038391

International Journal of Computational Biology and Drug Design, 2010 Vol.3 No.4, pp.259 - 270

Published online: 04 Feb 2011 *

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