Thin membrane with biomimetic hexagonal patterned surface for guided bone regeneration
by Anurag Satpathy; Rinkee Mohanty; Tapash Ranjan Rautray
International Journal of Nano and Biomaterials (IJNBM), Vol. 7, No. 4, 2018

Abstract: Polymeric membranes used as a barrier in guided tissue regeneration have undergone several modifications for improved structural, handling and biological properties. Biomaterial surface characteristics are critical in regulating cell function. Physicochemical signals from the substrate surfaces stimulate cell behaviour. This paper focuses on fabrication of biodegradable barrier membrane with hexagonal patterned surface for guided tissue regeneration. Hexagonal patterned surfaces were obtained during solvent casting of chitosan solution using a novel method. Obtained barrier membranes were analysed under stereo and electron microscopy and were assessed for their surface roughness. The hexagonal patterned surface barrier membranes had a significantly higher surface roughness (p < 0.001).

Online publication date: Wed, 26-Sep-2018

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