In vitro cytotoxicity and antibacterial studies of ruthenium(II) DMSO complexes with S-allyldithiocarbazate
by Selvakumar Ponnusamy; Narayanasamy Ramasamy
International Journal of Materials and Product Technology (IJMPT), Vol. 55, No. 1/2/3, 2017

Abstract: The ruthenium(II) DMSO complexes with formula [RuCl(DMSO)₃L₁](1) and [RuCl(DMSO)₃L₂](2) had been synthesised. The newly synthesised complexes are characterised by elemental analysis, UV-VIS, FT-IR, NMR and ESI-MS spectroscopy. The spectral and analytical data of the complexes 1 and 2 supports well with the molecular formulae proposed. The in vitro cytotoxicity of these complexes evaluated using MTT assay indicate that the above complexes are more toxic against Hela cervical cancer cell line, but significantly less toxic against the normal Vero cell line. Furthermore, the antibacterial activity of the complexes 1 and 2 against S.aureus and E.Coli had also been tested and compared with standard streptomycin.

Online publication date: Sun, 09-Jul-2017

The full text of this article is only available to individual subscribers or to users at subscribing institutions.

 
Existing subscribers:
Go to Inderscience Online Journals to access the Full Text of this article.

Pay per view:
If you are not a subscriber and you just want to read the full contents of this article, buy online access here.

Complimentary Subscribers, Editors or Members of the Editorial Board of the International Journal of Materials and Product Technology (IJMPT):
Login with your Inderscience username and password:

Username:        Password:          Forgotten your password?

Want to subscribe?
A subscription gives you complete access to all articles in the current issue, as well as to all articles in the previous three years (where applicable). See our Orders page to subscribe.

If you still need assistance, please email subs@inderscience.com