Liposome encapsulated gold nanoshells for NanoPhototherapy induced hyperthermia Online publication date: Fri, 11-Nov-2005
by Paul M. Kasili, Tuan Vo-Dinh
International Journal of Nanotechnology (IJNT), Vol. 2, No. 4, 2005
Abstract: Gold nanoshells have been extensively studied since their invention and their role in both in vitro and in vivo photothermal therapy has been explored and demonstrated. In this work, we investigate liposomal delivery of gold nanoshells and evaluate their effects for in vitro NanoPhototherapy induced hyperthermia in human mammary carcinoma cells. In addition, we compare the application of liposome encapsulated gold nanoshells and free standing gold nanoshells in NanoPhototherapy. NanoPhotoTherapy induced hyperthermia was performed using a 785 nm near-infrared light from a diode laser and the in vitro effects were evaluated using nucleic acid molecular probes by fluorescence microscopy. Additionally, we monitored apoptosis by detecting capase-9 activity.
Existing subscribers:
Go to Inderscience Online Journals to access the Full Text of this article.
If you are not a subscriber and you just want to read the full contents of this article, buy online access here.Complimentary Subscribers, Editors or Members of the Editorial Board of the International Journal of Nanotechnology (IJNT):
Login with your Inderscience username and password:
Want to subscribe?
A subscription gives you complete access to all articles in the current issue, as well as to all articles in the previous three years (where applicable). See our Orders page to subscribe.
If you still need assistance, please email subs@inderscience.com