Analysis of codon bias pattern for genome sequences through a three-phase network model
by Ahsan Z. Rizvi; C. Bhattacharya
International Journal of Signal and Imaging Systems Engineering (IJSISE), Vol. 9, No. 6, 2016

Abstract: Codon bias generates specific patterns of synonymous codons usage in genomes of all texta. Codon bias patterns of genomes are extracted here in spectral domain and named as Codon Bias Spectra (CBS). Such spectral models of codon bias are demonstrated through a three-phase network model of various genomes. GC, GC3 and AT3 bias patterns along with codon spectra are shown in the paper by modifying the parameters in this spectral model. Patterns of CBS are studied here for codon bias in prokaryotic genomes. Correlation and regression analysis of CBS show the influencing effects of GC, GC3 and AT3 bias. Analysis of the area under ROC curve (AUC) is performed for testing the statistical significance of the three-phase network model for identifying codon bias locations in genome.

Online publication date: Thu, 10-Nov-2016

The full text of this article is only available to individual subscribers or to users at subscribing institutions.

 
Existing subscribers:
Go to Inderscience Online Journals to access the Full Text of this article.

Pay per view:
If you are not a subscriber and you just want to read the full contents of this article, buy online access here.

Complimentary Subscribers, Editors or Members of the Editorial Board of the International Journal of Signal and Imaging Systems Engineering (IJSISE):
Login with your Inderscience username and password:

Username:        Password:          Forgotten your password?

Want to subscribe?
A subscription gives you complete access to all articles in the current issue, as well as to all articles in the previous three years (where applicable). See our Orders page to subscribe.

If you still need assistance, please email subs@inderscience.com