Influence of erythrocyte shape on platelet scattering towards vessel wall Online publication date: Sun, 14-Aug-2016
by Thakir D. Almomani; Suleiman Bani Hani; Ahmad Bdour; Amer A. Alsaraira; Othman Smadi; Ahmad Al-Jarrah; Rula Abdallat; Samer Awad
International Journal of Biomedical Engineering and Technology (IJBET), Vol. 21, No. 3, 2016
Abstract: Red Blood Cell (RBC) geometry forms unique distinguished shape. This shape is thought to have a major influence on both the function and the dynamics of the moving erythrocyte. The shape of the RBC is hypothesised to cause platelet scattering and diffusion towards vessel wall. The current study is built to provide a detailed review of the previous theories that discuss the influence of RBC shape on its functionality and dynamics, a detailed focus on the influence of RBC dynamics on platelet migration towards the vessel wall is presented. Afterwards, computational results representing the influence of RBC shape on platelet migration to the vessel wall are listed. The results involve comparison between circular and elliptical RBCs using low Reynolds number channel flow regime. It is shown that this migration process is primarily affected by the diameter of the RBC and not by its shape.
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