Directed self-organisation of soluble proteins on surfaces
by Marisela Velez
International Journal of Nanotechnology (IJNT), Vol. 2, No. 1/2, 2005

Abstract: Incorporation of proteins on surfaces is a first step in the lengthy process of using active biological molecules in man-made nanodevices. There is therefore a strong motivation to develop strategies for organising active proteins on solid substrates and it is very desirable to take advantage of the principles of self-assembly. In the present work, I summarise two strategies to orient and selectively adsorb proteins on gold surfaces previously modified with specially designed self-assembled monolayers. I also report on the on-going research describing the aggregating properties of a bacterial cytoskeletal protein on a surface to illustrate nature's ability to direct the self-assembly of dynamic structures.

Online publication date: Sat, 30-Apr-2005

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