Bioscaffolds development for small-diameter vascular grafts
by Nan Zhao; Donghui Zhu
International Journal of Biomedical Engineering and Technology (IJBET), Vol. 12, No. 2, 2013

Abstract: Cardiovascular diseases and injuries are one of the leading causes of mortality in the world. Vascular grafts implantation is the standard procedure to treat them, and there is a pressing need to develop small-diameter vascular vessels. Tissue engineering offers one promising approach to address the shortcoming of autologous therapies. Despite the successful application of polyethylene terephthalate (Dacron), polyurethane and Expanded Polytetrafluoroethylene (ePTFE) in large-diameter vascular grafts, the outcome of replacing the native small-diameter vessels by vascular grafts made from those biomaterials is still not satisfactory. Recent studies have shown some significant advances and provide confidence that success may be attainable in the near future. Here, we summarise recent development of bioscaffolds in Small-Diameter Vascular Grafts (SDVG) and discuss the challenges and potential improvements for the future.

Online publication date: Sat, 27-Sep-2014

The full text of this article is only available to individual subscribers or to users at subscribing institutions.

 
Existing subscribers:
Go to Inderscience Online Journals to access the Full Text of this article.

Pay per view:
If you are not a subscriber and you just want to read the full contents of this article, buy online access here.

Complimentary Subscribers, Editors or Members of the Editorial Board of the International Journal of Biomedical Engineering and Technology (IJBET):
Login with your Inderscience username and password:

Username:        Password:          Forgotten your password?

Want to subscribe?
A subscription gives you complete access to all articles in the current issue, as well as to all articles in the previous three years (where applicable). See our Orders page to subscribe.

If you still need assistance, please email subs@inderscience.com