Biomedical optical analytical techniques to analyse the medicinal drugs and optical properties of tissues
by G.S. Uthayakumar; A. Sivasubramanian
International Journal of Biomedical Engineering and Technology (IJBET), Vol. 12, No. 1, 2013

Abstract: In this research paper, the biomedical optical analytical techniques such as ultra-violet spectroscopy, Fourier transform infrared spectroscopy and Fourier transform-Raman spectroscopy are used to characterise and quantise the medicinal drugs. The hydroxyl group and methyl group was assigned to the wave numbers 3230.67 cm⁻¹ and 2928.50 cm⁻¹. The functional groups are also identified -N=C=O, -N=C=S, -N=C=N-, -N₃ at 4.67 μm. The CH, CH₂, and CH₃ three bands with strong intensity are assigned to the wave numbers 2985 cm⁻¹ to 2850 cm⁻¹. The FT-Raman spectra is obtained for the blue sample, the functional group C≡C is assigned to the wave number 2129.84 to 2191.41 cm⁻¹. The wave numbers 2558.71-2620.73 cm⁻¹ are obtained for the functional bond -S-H. The wave number 1610.95 cm⁻¹ is obtained for the C=N functional group. In this paper one sample namely Fibril-SF is taken by a patient and his saliva sample is collected for Fourier Transform Infrared spectroscopy test to analyse the reaction of drugs with human body tissues.

Online publication date: Sat, 27-Sep-2014

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