BoneNET: a network model of bone microstructure and dynamics
by Taehyong Kim; Lawrence Bone; Murali Ramanathan; Aidong Zhang
International Journal of Data Mining and Bioinformatics (IJDMB), Vol. 8, No. 2, 2013

Abstract: We develop a network model of bone microstructure and dynamics, BoneNET, which is capable of quantitative assessment of Bone Mineral Density (BMD) and bone remodelling dynamics. First, we introduce a network model of bone microstructure by describing structural properties and process of bone network modelling. Secondly, we explain a mathematical model of bone microstructure by analysing the density for mineralised fibres of bone microstructure. Finally, we provide a bone remodelling dynamics among osteoblast and osteoclast and study bone networks by proposing several measurements to calculate bone strength and identify critical elements in bone microstructure.

Online publication date: Mon, 20-Oct-2014

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