Protein contact map prediction using committee machine approach
by Narjeskhatoon Habibi; Mohamad Saraee; Hassan Korbekandi
International Journal of Data Mining and Bioinformatics (IJDMB), Vol. 7, No. 4, 2013

Abstract: Protein contact map is a simplified representation of a protein's spatial structure. The Committee Machine is a machine learning method that allots the learning task to a number of learners and divides the input space into subspaces. Learners' responses to an input are combined to produce the system's final response, which is more accurate than any single individual's response. In this study, we propose a novel method called CMP_model, for contact map prediction based on the committee machine. The results of the proposed model in comparison with two other models, show considerable gain (an accuracy improvement from 0.05 to 0.15).

Online publication date: Mon, 20-Oct-2014

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