Environmental exposure to pesticides: biomarkers in non-invasively collected matrices in prenatal development and childhood
by María Gabriela Rovedatti; Graciela Chiapella; Berta Vera; Gladis Griselda Magnarelli
International Journal of Environment and Health (IJENVH), Vol. 6, No. 1, 2012

Abstract: The collection of invasive samples from susceptible populations may suffer from ethical and practical limitations that restrict the routine application of human biomonitoring. Moreover, the accumulation of exposure data will be unsuccessful in risk assessment if not integrated through the appropriate sets of biomarkers for early biological responses. This paper reviews the usefulness and limitations of non-invasively collected matrices as well as common and novel biomarkers of effect for evaluating the impact of environmental exposure to pesticides in periods of high susceptibility to toxicants. We conclude that in the prenatal period, placenta and umbilical cord blood are matrices with vast potential, as saliva is for childhood biomonitoring. Thus, the development of better technology and the use of novel approaches may be useful strategies. Prospective studies that integrate the information from different matrices obtained throughout pregnancy and childhood, and their association with childhood diseases, are advantageous.

Online publication date: Sat, 12-May-2012

The full text of this article is only available to individual subscribers or to users at subscribing institutions.

 
Existing subscribers:
Go to Inderscience Online Journals to access the Full Text of this article.

Pay per view:
If you are not a subscriber and you just want to read the full contents of this article, buy online access here.

Complimentary Subscribers, Editors or Members of the Editorial Board of the International Journal of Environment and Health (IJENVH):
Login with your Inderscience username and password:

Username:        Password:          Forgotten your password?

Want to subscribe?
A subscription gives you complete access to all articles in the current issue, as well as to all articles in the previous three years (where applicable). See our Orders page to subscribe.

If you still need assistance, please email subs@inderscience.com