A pilot trial of onabotulinumtoxinA for the treatment of cervicothoracic myofascial pain
by Thomas L. Davis, John Y. Fang, Chandler E. Gill, P. David Charles
The Botulinum J. (TBJ), Vol. 2, No. 1, 2011

Abstract: This placebo-controlled crossover trial investigate the safety and efficacy of onabotulinumtoxinA (BOTOX, Allergan, Inc.) for the treatment of cervical myofascial pain syndrome (CMPS). A group of subjects with Cervical Dystonia (CD) served as additional controls. A change in diary pain score from baseline to week 3 in placebo vs. onabotulinumtoxinA was the primary outcome measure. Both CMPS and CD subjects showed a trend towards significant pain relief from onabotulinumtoxinA. This suggests that the study was underpowered and that a larger sample size would be necessary in future trials of onabotulinumtoxinA for CMPS.

Online publication date: Sat, 06-Aug-2011

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