Predicting vertebrate promoters using heterogeneous clusters Online publication date: Thu, 30-Sep-2010
by Fang-Yie Leu, Lun-Ni Yang, Neng-Wen Lo, I-Long Lin
International Journal of Ad Hoc and Ubiquitous Computing (IJAHUC), Vol. 6, No. 4, 2010
Abstract: This paper proposes a system, named the Vertebrate Promoter Prediction System (VePPS), which employs a new statistics-based approach to predict vertebrate promoters, and analyses a putative promoter sequence by investigating the presence of short promoter-specific sequences and known transcription factor binding sites. In comparison with other prediction programmes, our VePPS outperformed, e.g., promoter 2.0, by 38.0% and 12.7% in predicting promoter and non-promoter sequences, respectively.
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