Technological and socio-economic implications in the development of implantable drug infusion systems for cancer therapy in tricky anatomic compartments: the case of brain tumours
by Silvia Petroni, Dino Accoto, Barbara Labella, Giuseppe Turchetti, Eugenio Guglielmelli
International Journal of Biomedical Engineering and Technology (IJBET), Vol. 4, No. 4, 2010

Abstract: Effective administration of chemotherapeutics to the brain is a difficult task because of several reasons, including the anatomic location and the presence of the brain-to-blood barrier. The socio-economic burden of the pathology, discussed in the first part of the paper, stimulates the development of specific drug delivery systems, briefly reviewed and critically evaluated in a future perspective. Special emphasis is given to a solution under development at University Campus Bio-Medico (UCBM), which is compared to alternative approaches proposed in literature. Eventually, a technological roadmap is outlined and the related potential socio-economic impact is briefly discussed.

Online publication date: Thu, 30-Sep-2010

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