A more elaborative way to check codon quality: an open source program
by Rakesh Kumar Shardiwal, S.S. Sohrab
International Journal of Bioinformatics Research and Applications (IJBRA), Vol. 6, No. 3, 2010

Abstract: Relative Synonymous Codon Usage (RSCU) and Relative Adaptiveness of a Codon (RAC) table bias importance in gene expression are well documented in the literature. However, to improve the gene expression we need to figure out which codons are optimal for the expression in order to synthesise an appropriate DNA sequence. An alternative to the manual approach, which is obviously a tedious task, is to set up software on your computer to perform this. Though such kinds of programs are available on the internet, none of them are open-source libraries. Here, one can use our Perl program to do his or her task more easily and efficiently. It is free for everyone.

Online publication date: Wed, 07-Jul-2010

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