Lecture notes: 2010 and beyond, the decade of high-performance computing for the next-generation sequence analysis Online publication date: Sat, 03-Oct-2009
by Mary Qu Yang, Jack Y. Yang
International Journal of Computational Biology and Drug Design (IJCBDD), Vol. 2, No. 2, 2009
Abstract: Effective analysis of the next-generation sequence relies on the intelligent algorithms for handling the meta-genome, epigenetic and disease genome, as well as immune-genome, viral profiling, transcriptome profiling, and de novo genome sequencing data, therefore, next-generation sequence analysis is a very important but challenging task in bioinformatics due to extremely large-scale 'noisy' datasets. We focus mainly on the development of high-performance genetic algorithms based on multi-core technology as an example and open to fast-moving competing platforms to be emerged.
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