Lengthened duration of benefit from botulinum toxin injections for the treatment of spasticity
by Chandler E. Gill, CaraLee R. Blair, Michael S. Putman, Henry M. Taylor, P. David Charles
The Botulinum J. (TBJ), Vol. 1, No. 2, 2008

Abstract: In the setting of a spasticity management program, 26 adults with Intellectual Disability (ID) and spasticity were treated with injections of Botulinum Toxin type A. After a series of regular injections (range: 4-7 injections), three patients experienced dramatically lengthened benefit lasting an average of 22.3 months (range: 19-29). None of the patients exhibit characteristics that have been suggested to explain this phenomenon in other disorders, such as duration of illness or toxin dose. Future studies should identify which characteristics or treatment parameters predict lengthened response.

Online publication date: Tue, 16-Jun-2009

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