Experimental studies on the biological effects of low-dose-rate and low-dose radiation
by Yoichi Oghiso, Satoshi Tanaka, Ignacia B. Tanaka III, Fumiaki Sato
International Journal of Low Radiation (IJLR), Vol. 5, No. 1, 2008

Abstract: A lifespan study using a total of 4000 adult Specific Pathogen-Free (SPF) mice indicated that continuous gamma-ray exposures of both females and males for approximately 400 days at a dose rate of 20 mGy/day induced significant life shortening, mainly due to early neoplastic death, but no significant differences were found after exposure at a dose rate of 0.05 mGy/day as compared to nonexposed controls. Based on these results, we are working on several research projects on the biological effects of low-dose-rate and low-dose radiation exposures in mice to assess the risk of genetic effects, and to make clear the cellular and molecular mechanisms for the biological consequences, such as cancers and noncancer diseases, of the continuous low-dose-rate radiation exposures.

Online publication date: Wed, 18-Jun-2008

The full text of this article is only available to individual subscribers or to users at subscribing institutions.

 
Existing subscribers:
Go to Inderscience Online Journals to access the Full Text of this article.

Pay per view:
If you are not a subscriber and you just want to read the full contents of this article, buy online access here.

Complimentary Subscribers, Editors or Members of the Editorial Board of the International Journal of Low Radiation (IJLR):
Login with your Inderscience username and password:

Username:        Password:          Forgotten your password?

Want to subscribe?
A subscription gives you complete access to all articles in the current issue, as well as to all articles in the previous three years (where applicable). See our Orders page to subscribe.

If you still need assistance, please email subs@inderscience.com