Automated segmentation and classification of nuclei in histopathological images Online publication date: Thu, 07-Apr-2022
by Sanjay Vincent; J. Chandra
International Journal of Biomedical Engineering and Technology (IJBET), Vol. 38, No. 3, 2022
Abstract: Various kinds of cancer are detected and diagnosed using histopathological analysis. Recent advances in whole slide scanner technology and the shift towards digitisation of whole slides have inspired the application of computational methods on histological data. Digital analysis of histopathological images has the potential to tackle issues accompanying conventional histological techniques, like the lack of objectivity and high variability. In this paper, we present a framework for the automated segmentation of nuclei from human histopathological whole slide images, and their classification using morphological and colour characteristics of the nuclei. The segmentation stage consists of two methods, thresholding and the watershed transform. The features of the segmented regions are recorded for the classification stage. Experimental results show that the knowledge from the selected features is capable of classifying a segmented object as a candidate nucleus and filtering out the incorrectly identified segments.
Existing subscribers:
Go to Inderscience Online Journals to access the Full Text of this article.
If you are not a subscriber and you just want to read the full contents of this article, buy online access here.Complimentary Subscribers, Editors or Members of the Editorial Board of the International Journal of Biomedical Engineering and Technology (IJBET):
Login with your Inderscience username and password:
Want to subscribe?
A subscription gives you complete access to all articles in the current issue, as well as to all articles in the previous three years (where applicable). See our Orders page to subscribe.
If you still need assistance, please email subs@inderscience.com
Our Blog 
Follow us on Twitter 
Visit us on Facebook