Numerical assessment of a 3D human upper respiratory tract model: effect of anatomical structure on asymmetric tidal pulmonary ventilation characteristics
by Digamber Singh; Anuj Jain; Akshoy Ranjan Paul
International Journal of Biomedical Engineering and Technology (IJBET), Vol. 38, No. 3, 2022

Abstract: The analysis of airway ventilation characteristic is important for diagnosis and pathological assistance for respiratory diseases. It is therefore imperative to study the impact of anatomical features on the internal flow field. The article is focused on an in-silico study on impact of anatomical structure of human upper respiratory tract on transient asymmetric tidal pulmonary ventilation characteristics. Therefore, a three-dimensional human airways model is reconstructed from nasal cavity up to seventh generation bronchi from computed tomography (CT) images of a 48-year-old healthy man using computational modelling technique. A validated low Reynolds number (LRN) realisable k - ε turbulence model is used to capture the internal flow mixed turbulence characteristics. The numerical simulations were performed for asymmetric low and high tidal pulmonary ventilation (ALTPV, 10 L/min and AHTPV, 40 L/min). The numerical analysis assists to predict the near realistic airway ventilation phenomena and internal flow physics in the upper respiratory tract.

Online publication date: Thu, 07-Apr-2022

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