Clustering analysis on molecular docking with swarm intelligence
by E. Kiruba Nesa Malar; C.P. Chandran
International Journal of Advanced Intelligence Paradigms (IJAIP), Vol. 20, No. 1/2, 2021

Abstract: In this work, clustering analysis on molecular docking using swarm intelligence is carried out with molecular docking assessment of DNA-ligand interaction using cancer dataset. In this work, we have used docking to perform DNA-ligand interaction. Fuzzy C-means clustering (FCM) is a method of clustering which allows one piece of data to belong to two or more clusters. Glowworm swarm optimisation (GSO) is a current nature-stimulated optimisation algorithm that simulates the conduct of the lighting fixtures worms. Datasets are taken from PDB and drug bank and tested on DNA-ligand interaction with a cancer dataset. The performance of this work is tested on ten docking instances from the PDB bind core set and compared to the performance of three algorithms. The results show that the combined work could find ligand poses with best energy levels.

Online publication date: Thu, 16-Sep-2021

The full text of this article is only available to individual subscribers or to users at subscribing institutions.

 
Existing subscribers:
Go to Inderscience Online Journals to access the Full Text of this article.

Pay per view:
If you are not a subscriber and you just want to read the full contents of this article, buy online access here.

Complimentary Subscribers, Editors or Members of the Editorial Board of the International Journal of Advanced Intelligence Paradigms (IJAIP):
Login with your Inderscience username and password:

Username:        Password:          Forgotten your password?

Want to subscribe?
A subscription gives you complete access to all articles in the current issue, as well as to all articles in the previous three years (where applicable). See our Orders page to subscribe.

If you still need assistance, please email subs@inderscience.com