Application of rehabilitation of cruciate ligament injury during exercise based on nano-biomaterials tissue engineering treatment plan Online publication date: Tue, 13-Apr-2021
by Yingjie Shi
International Journal of Nanotechnology (IJNT), Vol. 18, No. 1/2/3/4, 2021
Abstract: The development and application of biomaterial tissue engineering technology provide new ideas and approaches in the rehabilitation of a cruciate ligament injury. Polyvinyl alcohol (PVA) fibre meets biosafety requirements, has no toxicity, no irritation, no genotoxicity, no carcinogenicity, and good biocompatibility to the human body. This study investigated and verified the growth of the human anterior cruciate ligament (hACL) cells on the ligament scaffold material PVA. This study shows that a PVA fibre as a tissue engineering scaffold ligament, cultured hACL cells in vitro proliferative capacity and a strong ability to secrete collagen matrix. The scaffold material has good cell compatibility, has certain swelling and mechanical properties, and is expected to develop into an ideal tissue for engineering anterior cruciate ligament scaffold material for rehabilitation treatment of a cruciate ligament injury during exercise.
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