Development of a microfluidic flow-focusing droplet generating device utilising rapid prototyping technique Online publication date: Fri, 20-Nov-2020
by Loc Pham Xuan; Loc Do Quang; Tuan Vu Quoc; Cuong Nguyen Nhu; Hang Nguyen Thu; Hang Tran Thanh; An Nguyen Ngoc; Tung Thanh Bui; Trinh Chu Duc
International Journal of Nanotechnology (IJNT), Vol. 17, No. 7/8/9/10, 2020
Abstract: In the recent decades, droplet-based microfluidics has emerged as a promising research area which covers various applications in a broad spectrum of fields such as chemical reactions, drug discovery, molecule synthesis and cell biology. This study proposes the implementation of a microfluidic droplet generating prototype using the popular flow-focusing geometry. The proposed system is fabricated based on a rapid prototyping technique, which significantly simplifies the fabrication process, reduces the production cost and shortens the time-to-market as compared with traditional techniques. The functionalities and characteristics of the prototype were carefully verified by simulations and practical experiments. The obtained results showed that the generation of droplets could be precisely controlled by adjusting the flow rate ratio between the dispersed phase and the continuous phase.
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