Design of analytic wavelet transform with optimal filter coefficients for cancer diagnosis using genomic signals
by Deepa Grover; Sonica Sondhi; Benoy Banerji
International Journal of Biomedical Engineering and Technology (IJBET), Vol. 34, No. 2, 2020

Abstract: DNA sequence analysis and gene expression analysis through genomic signal processing played an important role in cancer diagnosis in recent years. Cancer diagnosis through gene expression data, discrete Fourier transform, discrete wavelet transform (DWT) and IIR low pass filter are frequently used but suffer from drawbacks like longer essential time-support. Analytic wavelet transform with optimal filter coefficients for cancer diagnosis using genomic signals is designed in this paper. The proposed technique consists of three modules namely, pre-processing module, optimisation module and transform and cancer diagnosis module. Initially, the filter coefficients are optimally found out using group search optimiser. Then, the optimal coefficients and the pre-processed DNA sequence is applied to analytic wavelet transform and subsequently, diagnosis for the cancer cell is made based on the threshold. DNA sequences obtained from National Centre for Biotechnology Information (NCBI) forms the database for the evaluation. Evaluation metrics parameters employed are sensitivity, specificity and accuracy. Comparison is made to the base method and analytic transform technique for more analysis. From the results, we can observe that the proposed technique has achieved good results attaining accuracy of 91.6% which is better than other compared techniques.

Online publication date: Thu, 05-Nov-2020

The full text of this article is only available to individual subscribers or to users at subscribing institutions.

 
Existing subscribers:
Go to Inderscience Online Journals to access the Full Text of this article.

Pay per view:
If you are not a subscriber and you just want to read the full contents of this article, buy online access here.

Complimentary Subscribers, Editors or Members of the Editorial Board of the International Journal of Biomedical Engineering and Technology (IJBET):
Login with your Inderscience username and password:

Username:        Password:          Forgotten your password?

Want to subscribe?
A subscription gives you complete access to all articles in the current issue, as well as to all articles in the previous three years (where applicable). See our Orders page to subscribe.

If you still need assistance, please email subs@inderscience.com