Optimisation of carbon nanotubes for advanced diagnosis and biomedical application
by Khalid Parwez; Suman Veerappa Budihal
International Journal of Nanoparticles (IJNP), Vol. 11, No. 3, 2019

Abstract: Nanomaterials have a broad spectrum of applications in biomedical fields. The carbon nanotubes (CNTs) are among the most versatile and well-characterised members of this group of materials. This review aims to discuss how to utilise CNTs as a diagnostic tool. Functionalisation with antibodies has gained significance in recent years among the various way of functionalisation of CNTs. Antibodies make their surface sensitive to surroundings for immuno-sensing. Surface passivation with other proteins is required to inhibit the non-specific binding of biomolecules on the hydrophobic carbon nanotube surface for ultrasensitive detection of biological species. CNT-based immuno-sensors provide excellent results with a promising sensitivity and reproducibility and, in combination with novel devices [such as a microfluidic electrochemical biosensor, nanoelectromechanical systems (NEMS), paper-based analytical devices (PADs), field effect transistors (FET)]. This combination offers an attractive analytical approach for the fast, low-cost, and accessible detection of trace prognostic biomarkers, microbial pathogens, environmental pollutants, and toxins.

Online publication date: Mon, 30-Sep-2019

The full text of this article is only available to individual subscribers or to users at subscribing institutions.

 
Existing subscribers:
Go to Inderscience Online Journals to access the Full Text of this article.

Pay per view:
If you are not a subscriber and you just want to read the full contents of this article, buy online access here.

Complimentary Subscribers, Editors or Members of the Editorial Board of the International Journal of Nanoparticles (IJNP):
Login with your Inderscience username and password:

Username:        Password:          Forgotten your password?

Want to subscribe?
A subscription gives you complete access to all articles in the current issue, as well as to all articles in the previous three years (where applicable). See our Orders page to subscribe.

If you still need assistance, please email subs@inderscience.com