Article Abstract

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Title: |
Cellunomics: the interaction analysis of cells |
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Author: |
Virendra S. Gomase, Aravind K. Tripathi, Somnath Tagore
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Address: |
Department of Bioinformatics, Padmashree Dr. D.Y. Patil University, Plot No. 50, Sector 15, CBD Belapur, Navi Mumbai 400614, India. ' Department of Bioinformatics, Padmashree Dr. D.Y. Patil University, Plot No. 50, Sector 15, CBD Belapur, Navi Mumbai 400614, India. ' Department of Bioinformatics, Padmashree Dr. D.Y. Patil University, Plot No. 50, Sector 15, CBD Belapur, Navi Mumbai 400614, India |
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Journal: |
International Journal of Bioinformatics Research and Applications 2009 - Vol. 5, No.6 pp. 674 - 690 |
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Abstract: |
Cellunomics envisions the new branch of cell, which integrates genomics and proteomics with a new knowledge base built from temporal and spatial data on the chemical and molecular interrelationships of cellular components, i.e., cellome. Cellunomics helps in finding cell-specific protein and protein-protein interaction using cell-specific mRNA and protein repository. A flexible statistical-model-based clustering approach is introduced for identifying cell populations and the data revealed by the cellome is informational as well as physical. Cellunomics aids the automated, high-content platforms, to increase the scope and scale of experiments traditionally executed through interactive microscopy. |
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Keywords: |
cellome; chromatography; clustering; electrophoresis; signalling; spectrometry; cell interactions; cellunomics; genomics; proteomics; cellular components; cell-specific protein; protein-protein interaction; bioinformatics. |
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DOI: |
10.1504/IJBRA.2009.029046 |
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