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Title: |
Computer simulation of intracardiac potential with whole-heart model |
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Author: |
Xin Zhu, Daming Wei 
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Address: |
Graduate Department of Information Systems, University of Aizu, Aizu-Wakamatsu City, Fukushima Prefecture 965-8580, Japan. ' Graduate Department of Information Systems, University of Aizu, Aizu-Wakamatsu City, Fukushima Prefecture 965-8580, Japan |
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Journal: |
International Journal of Bioinformatics Research and Applications 2007 - Vol. 3, No.1 pp. 100 - 122 |
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Abstract: |
Computer simulation of intracardiac potentials was performed based on a whole-heart model, emphasising applications to Electrophysiology Study (EPS) and catheter ablation. A numerical method was proposed based on a volume conductor model with multiple interfaces and piecewise homogeneity. A model of a normal heart and a model of Wolff-Parkinson-White (WPW) Syndrome with a right free-wall Accessory Pathway (AP) were employed to simulate intracardiac electrograms. The study was validated by comparing the simulated electrograms with those in catheter-based EPS and ablations. Applying whole-heart modelling to the EPS and ablation is regarded as a new direction of electrocardiologic forward problem. |
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Keywords: |
electrophysiology study; EPS; catheter ablation; intracardiac potential; whole-heart model; computer simulation; forward problem; Wolff-Parkinson-White syndrome; WPW syndrome; bioinformatics; intracardiac electrograms; heart modelling. |
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DOI: |
10.1504/IJBRA.2007.011837 |
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