The full text of this article
Tunable resistive pulse sensing and nanoindentation of pH-responsive expansile nanoparticles
by Eva Weatherall; Thomas Loho; Michelle Dickinson; Aaron H. Colby; Mark W. Grinstaff; Geoff R. Willmott
International Journal of Nanotechnology (IJNT), Vol. 14, No. 1/2/3/4/5/6, 2017
Abstract: Experimental studies of pH-responsive expansile nanoparticles (eNPs) have been carried out using tunable resistive pulse sensing (TRPS) and nanoindentation. The eNPs are initially ∼200 nm in diameter, but increase in size owing to a compositional change resulting from cleavage of pH-labile protecting groups on the polymer backbone at low pH. TRPS detected expected changes in the size of eNPs, most clearly through an increase in the size distribution close to ∼1 μm diameter with time after exposure to pH 5.0 electrolyte. Heavily cross-linked nanoparticles and eNPs kept at neutral pH did not produce such pronounced changes. Nanoindentation results demonstrate that for accurate measurement of eNP mechanical properties, particles must be precisely located and securely fixed to the substrate. Moreover, the expanded eNPs may be too weak to respond to conventional nanoindentation. Nanoscale physical characterisation of soft matter is of burgeoning importance in medical and biotechnological research and applications.
Online publication date: Mon, 20-Feb-2017
is only available to individual subscribers or to users at subscribing institutions.
Go to Inderscience Online Journals to access the Full Text of this article.
Pay per view:
If you are not a subscriber and you just want to read the full contents of this article, buy online access here.
Complimentary Subscribers, Editors or Members of the Editorial Board of the International Journal of Nanotechnology (IJNT):
Login with your Inderscience username and password:
Want to subscribe?
A subscription gives you complete access to all articles in the current issue, as well as to all articles in the previous three years (where applicable).
See our Orders page to subscribe.
If you still need assistance, please email firstname.lastname@example.org