An edge-driven 3D region-growing approach for upper airway morphology and volume evaluation in patients with Pierre Robin sequence
by Carmelo Militello; Salvatore Vitabile; Leonardo Rundo; Cesare Gagliardo; Sergio Salerno
International Journal of Adaptive and Innovative Systems (IJAIS), Vol. 2, No. 3, 2015

Abstract: Pierre Robin sequence (PRS) is a pathological condition responsible for a sequence of clinical events, such as breathing and feeding difficulties, that must be addressed to give the patient at least a chance to survive. By using medical imaging techniques, in a non-intrusive way, the surgeon has the opportunity to obtain 3D views, reconstruction of the regions of interest (ROIs), useful to increase understanding of the PRS patient's condition. In this paper, a semi-automatic approach for segmentation of the upper airways is proposed. The implemented approach uses an edge-driven 3D region-growing algorithm to segment ROIs and 3D volume-rendering technique to reconstruct the 3D model of the upper airways. This method can be used to integrate information inside a medical decision support system, making it possible to enhance medical evaluation. The effectiveness of the proposed segmentation approach was evaluated using Jaccard (92.1733%) and Dice (94.6441%) similarity indices and specificity (96.8895%) and sensitivity (97.6682%) rates. The proposed method achieved an average computation time reduced by a 16x factor with respect to manual segmentation.

Online publication date: Wed, 27-Jan-2016

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