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Non-invasive glucose monitoring using impedance spectroscopy
by Shruti Narasimham; Gaurav Kaila; Sneh Anand
International Journal of Biomedical Engineering and Technology (IJBET), Vol. 14, No. 3, 2014
Abstract: Continuous blood glucose monitoring provides maximal information about shifting blood glucose levels and facilitates optimal treatment decisions for the diabetic patient, by identifying and preventing unwanted episodes of hypoglycaemia and hyperglycaemia. Non-invasive techniques provide comfort and easier accessibility to the user in comparison to the invasive blood glucose monitoring systems. This paper presents a novel approach towards non-invasive glucose monitoring via impedance spectroscopy. Impedance spectroscopy refers to measurement of dielectric properties of the medium with change in frequency. Changing blood glucose levels affects its dielectric characteristics which changes blood impedance. Blood is modelled in the form of Ringer's solution and tested using Ag/AgCl reference electrodes. Four-electrode impedance measurement is used to assess impedance changes as a function of frequency. With changes in glucose concentration in the solution, subsequent readings of impedance are recorded and the correlations provide a proof of change in blood impedance with glucose level fluctuations.
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