The full text of this article


A novel ANFIS application for prediction of post-dialysis blood urea concentration
by Ahmad Taher Azar
International Journal of Intelligent Systems Technologies and Applications (IJISTA), Vol. 12, No. 2, 2013


Abstract: Dialysis dose (Kt/V) is mostly dependent on dialysis kinetic variables such as pre-dialysis and post-dialysis blood urea nitrogen concentration (Cpost), ultrafiltration (UF) volume, duration of the dialysis procedure, and urea distribution volume. Therefore, post-dialysis blood urea concentration is used to assess the dialysis efficiency. It gradually decreases to about 30% of the pre-dialysis value depending on the urea clearance rate during the period of dialysis. If the urea removal is inadequate, then dialysis is inadequate. This paper proposes a novel method, Adaptive Neuro-Fuzzy Inference System (ANFIS) to predict the post-dialysis blood urea concentration. The advantage of this neuro-fuzzy hybrid approach is that it does not require the model structure to be known a priori, in contrast to most of the urea kinetic modelling techniques. The accuracy of the ANFIS was prospectively compared with other traditional methods for predicting single pool dialysis dose (spKt/V). The results are highly promising, and a comparative analysis suggests that the proposed modelling approach outperforms other traditional urea kinetic models (UKM).

Online publication date: Fri, 30-Aug-2013


is only available to individual subscribers or to users at subscribing institutions.

Existing subscribers:
Go to Inderscience Online Journals to access the Full Text of this article.

Pay per view:
If you are not a subscriber and you just want to read the full contents of this article, buy online access here.

Complimentary Subscribers, Editors or Members of the Editorial Board of the International Journal of Intelligent Systems Technologies and Applications (IJISTA):
Login with your Inderscience username and password:


    Username:        Password:         

Forgotten your password?

Want to subscribe?
A subscription gives you complete access to all articles in the current issue, as well as to all articles in the previous three years (where applicable). See our Orders page to subscribe.

If you still need assistance, please email